Genesis of Personalized Medicine & Research Concept
The information contained herein is intended to provide a basic foundation for the scientifically verifiable processes that enable the evolution of personalized medicine and revolutionize clinical research and development.
How did we evolve to offer unparalleled IP for personalized medicine?
While working on the dynamics of logic and emotion in decision making and the cognitive processes associated with change inertia, the efforts of the members of The Center led them into the study of neurohormones.
This process identified unique corollary relationships between neurohormones. Intrigued by these apparent patterns, the team added a research biologist and formed a separate Life Sciences group to determine if the pattern would also apply to genes (proteins). The group called upon advisors in chemistry and physics to ensure that the pattern was consistent throughout all of the physical sciences.
It became apparent that the "model" could be applied to scientific processes for maintaining equilibrium (balance or homeostasis) throughout a network of substances within the body.
By formulating and applying its Epigenetic Model for Homeostasis (EMH) to existing scientific principles, The Center's Life Sciences group has identified the scientifically verifiable, explicit explanation for the biological dynamics of gene expression; i.e. the "off and on" mechanisms necessary to support the balance (homeostasis) of substances in the body as well as the mechanisms associated with the need to accomplish "gene silencing."
Applying The Center's model to personalized medicine and research
The science of epigenetics has evolved as the future for medical research because DNA research has not addressed all of the compositional substances in the body (e.g. lipids, carbohydrates and minerals).
A recent article in Time Magazine explained the emphasis on epigenetics as the new frontier of research into the causal paths of illnesses and diseases. http://www.time.com/time/health/article/0,8599,1951968,00.html
Applying its EMH as part of retrospective review of scientific literature has enabled the Center's Life Sciences group to identify causal paths for numerous chronic disease states. As part of their findings, the group has created explicit diagnostic assessment tools for illnesses and diseases that serve as the foundation from which enable pharmaceutical manufacturers to formulate new medications and treatment regimens.
Among the intellectual property developed by The Center are multiple pending patent applications for theranostic (predictive diagnostic tests) and new medical devices that transform current biodiagnostic testing methods.
In addition to amassing a comprehensive portfolio of intellectual property relative to causal paths of numerous chronic disease states, The Center has documented more that two hundred observations and findings that warrant detailed research as part of epigenetics. This material is available to those seeking to develop pipelines for medications that address personalized medicine.
Due to the complexity of the many models relative to the transformation of medical research, they cannot be explained within this web site. Accordingly, specific questions or inquiries regarding the work of The Center's Life Sciences group relative to research applications should be directed to Matthew Gyulay at: mgyulay@TheCenterNJ.com